Delysid (LSD 25)
D-lysergic acid diethylamide tartrate
Sugar-coated tablets containing 0.025 mg. (25 µg.).
Ampoules of 1 ml. containing 0.1 mg. (100 µg.) for oral administration.
The solution may also be injected s.c. or i.v. The effect is identical with that of oral administration but sets in more rapidly.
The absorption of the solution is somewhat more rapid and more constant that that of the tablets.
Ampoules which have not been opened, which have been protected against light and stored in a cool place are stable for an unlimited period. Ampoules which have been opened or diluted solutions retain their effectiveness for 1 to 2 days, if stored in a refrigerator.
b) Experimental studies on the nature of psychoses: By taking Delysid himself, the psychiatrist is able to gain an insight in the world of ideas and sensations of mental patients. Delysid can also be used to induced model psychoses of short duration in normal subjects, this facilitating studies on the pathogenesis of mental disease.
In normal subjects, doses of 25 to 75 µg. are generally sufficient to produce a hallucinatory psychosis (on an average 1 µg./kg. body weight). In certain forms of psychosis and in chronic alcoholism, higher doses are necessary (2 to 4 µg./kg. body weight).
Delysid should only be administered under strict medical supervision. The supervision should not be discontinued until the effects of the drug have completely worn off.
Literature available on request.
SANDOZ LTD., BASLE, SWITZERLAND
From the product monograph.